Bispecific Antibodies

Antibodies, often monoclonal, in which the two antigen-binding sites are specific for separate ANTIGENIC DETERMINANTS. They are artificial antibodies produced by chemical crosslinking, fusion of HYBRIDOMA cells, or by molecular genetic techniques. They function as the main mediators of targeted cellular cytotoxicity and have been shown to be efficient in the targeting of drugs, toxins, radiolabeled haptens, and effector cells to diseased tissue, primarily tumors.

Also Known As:

Antibodies, Bispecific; Bispecific Monoclonal Antibodies; Antibodies, Bifunctional; Antibodies, Bispecific Monoclonal; Monoclonal Antibodies, Bispecific; Bifunctional Antibodies

Pharmalogical Action Categories:

Immunologic Factors

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Blood Proteins: 12459
    - Serum Globulins: 553
      - Immunoglobulins: 30480
        Antibodies: 133716
        Bispecific Antibodies: 968
    - Immunoproteins: 43
      - Immunoglobulins: 30480
        Antibodies: 133716
        Bispecific Antibodies: 968
  - Globulins: 3062
    - Serum Globulins: 553
      - Immunoglobulins: 30480
        Antibodies: 133716
        Bispecific Antibodies: 968

P Holliger Selected Research

P Holliger Research Topics

Disease

Drug/Important Bio-Agent (IBA)

Therapy/Procedure